Articles Tagged with: hair miniaturization

Creatine Linked with Hair Loss

Creatine-Linked-with-Hair-LossMen and women who take creatine monohydrate might soon see signs of hair loss. According to a study published by the Clinical Journal of Sport Medicine, creatine use has been linked with hair loss among individuals taking the popular exercise supplement. The primary mechanism of hair loss is increased production of DHT among creatine users, a well-documented precursor to pattern baldness.

What is Creatine?

Contrary to popular belief, creatine is naturally produced by the human body. It is formed primarily by the kidney and liver, though not in the doses available via popular weight training supplements. In the body, creatine is a non-essential nutrient produced by L-arginine, glycine, and L-methionine that helps muscles form ATP to produce energy.

Because it serves a vital role in the production of energy, creatine has become a popular weight lifting supplement that men and women use to enhance strength and endurance while exercising. A large body of research has positively correlated creatine supplementation and strength gain since the late 1970s, making the supplement wildly popular among male and female athletes looking for a relatively “safe” edge in the gym.

But does creatine cause hair loss? According to new studies, there is reason to think it might.

Creatine and Hair Loss

The link between creatine and hair loss is still being studied. In one of the most talked-about studies, creatine supplementation was correlated with a 56% increase in DHT production (i). The conversion of testosterone to DHT has been strongly correlated with hair miniaturization, a phenomenon that causes hair follicles to slowly become incapable of supporting natural hair growth. Hair miniaturization is thought to be one of the main causes of pattern baldness in both men and women.

The Rugby Institute of South Africa served as the backdrop for this creatine and hair loss study. Additional information on this study:

Study: Double-blind, placebo-controlled.

Subjects: Rugby players volunteered for the study. All participants were of college age.

Dosage: Creatine dosage consisted of a loading phase and maintenance phase, which is commonly recommended by manufacturers of recreational creatine supplements. Loading phase lasted 7 days and consisted of 25 grams/day along with 25 grams of sugar (glucose). Maintenance phase consisted of 14 consecutive days immediately following loading phase, with participants receiving 5 grams/day with 25 grams sugar (glucose).

Placebo: Control group given just sugar.

Results: Testosterone levels remained constant throughout both loading and maintenance phases. Among participants given creatine, DHT levels increased about 57% after loading phase. During maintenance phase, participants taking creatine exhibited DHT levels about 40% above baseline.

Followup Reading: Visit the Clinical Journal of Sport Medicine in the sources section below to read the original study.

Hair Loss Consultation in Miami

Don’t let hair loss cause social, professional, or personal anxiety. At the Hair Transplant Institute of Miami, we hold your pursuit of a new and full head of hair in the highest regard. We proudly offer South Florida residents with the most advanced and comprehensive hair loss treatments available.

To learn more about hair loss evaluations and treatments, contact our Institute online or call directly 305-925-0222.

Sources:

(i) Clinical Journal of Sport Medicine. Issue: Volume 19(5), September 2009, pg. 399-404.

Take Rogaine® or Aspirin, Never Both

Take Rogaine® or Aspirin, Never BothA new study has shown that men and women who take Rogaine® (Minoxidil) to treat hair loss might want to consider keeping the aspirin bottle capped. A research team at the University of British Columbia has found evidence that the popular anti-inflammatory medication may suppress the same enzymes that Rogaine seeks to stimulate, thereby negating the effect of the popular hair loss treatment. This discovery is potentially alarming for many Rogaine users, as daily Aspirin use is widely promoted by physicians as a safe way to improve cardiovascular health and reduce the chance of heart attack and stroke.

In light of this recent finding, men and women who regularly use Rogaine may wish to find alternative methods of improving cardiovascular health. Alternatively, hair loss sufferers may elect to continue taking Aspirin and choose to restore areas of balding scalp via hair transplant. Unfortunately, evidence suggests one can no longer do both.

How Rogaine® Works

Minoxidil, available by the brand name Rogaine, is one of the most widely used non-surgical treatments for hair loss. Though it is still unclear exactly how the topical foam suppresses hair loss, many studies indicate that Rogaine stimulates the production of a very special enzyme called cyclooxygenase1, or COX-1. As the production of COX-1 increases, so too does the production of prostaglandin E2, or PGE2.

Increased levels of PGE2 has a very positive impact on the overall health and functionality of hair follicles, and in some cases may reverse the process of hair miniaturization. Hair miniaturization is characterized by the inability of hair follicles to sustain natural hair growth, a phenomenon that may eventually lead to pattern baldness, or androgenetic alopecia. In this way, Rogaine is thought to reverse the signs of hair loss by stabilizing hair follicles through increased production of PGE2.

How Aspirin May Hinder the Effects of Rogaine

Unfortunately, a ground-breaking new study released by the Department of Dermatology and Skin Science at the University of British Columbia demonstrates that Aspirin may negate the effects of Rogaine, simply by acting as an anti-inflammatory. Specifically, Aspirin suppresses the synthesis of certain prostaglandins by actively shutting-down cyclooxygenase enzymes like COX-1.

Just as Rogaine seeks to stimulate COX-1 production to improve hair growth, Aspirin disables COX-1 to fight inflammation.

Alternative Hair Loss Treatments

Fortunately, there are alternatives to Rogaine that may restore areas of balding scalp with all-natural hair. Two leading methods include follicular unit extraction (FUE) transplant, and a robotics-assisted transplant with the all-new ARTAS® System.

FUE Hair Transplant. FUE transplants are conducted by highly qualified surgeon. The scalp is anesthetized prior to the procedure, so almost no pain is experienced by the patient. Individual clusters of hair follicles are then removed from the patient’s own scalp, using a minimally invasive “punch” instrument that measures only a few millimeters in diameter. The surgeon then separates the clusters into pairings of 1-3 hairs and expertly transplants them to the area of balding scalp, by hand.

ARTAS® System Transplant. The Hair Transplant Institute of Miami has recently become 1 of fewer than 20 clinics to offer the revolutionary new ARTAS System, the first ever FDA approved robotics technology for FUE transplant procedures. Using the ARTAS, our surgeons are able to perform FUE transplants with more quickly, with greater accuracy and precision. Recovery time is faster than ever, and the end-result is incredibly natural in appearance. Learn more about ARTAS hair transplants in Miami.

This exclusive health report has been published by the Hair Transplant Institute of Miami. For additional information or appointment requests, please call toll-free 1-877-443-9070.

PCOS and Hair Loss

PCOS and Hair LossPolycystic ovary syndrome, or PCOS, is a hormonal condition that physicians attribute to both genetic and environmental factors. It is fairly common, affecting an estimated 10% of women worldwide (i). Primarily, PCOS is known to cause hormonal variations that may make it difficult to get pregnant. However, PCOS may cause additional side effects including weight gain, acne, and hair loss. Over time, studies indicate women with untreated PCOS may be at high risk for developing other serious health conditions like type II diabetes and heart disease.

Diagnosing PCOS

PCOS is perhaps the most common of all endocrine (hormonal) disorders experienced by females of reproductive age, and it is believed to be the leading cause of infertility among women. An estimated 50% of women with PCOS do not know they have the condition. In light of this alarming statistic, it is important to spread awareness for the symptoms of PCOS so proactive measures can be taken to reduce its impact on overall physical and emotional health.

Common symptoms of PCOS include:

  • Acne
  • Uncontrollable fluctuations in weight (gain or loss)
  • Increased growth of facial and/or body hair
  • Irregular menstruation cycles
  • Infertility / difficulty conceiving
  • Emotional distress, including depression
  • Thinning, shedding, or balding of the scalp

PCOS and Hormonally Induced Female Hair Loss

The defining physical characteristic of PCOS is ovarian cysts, tiny growths that appear throughout the ovaries. While the cysts themselves are not harmful, they do impair the production of an essential ovarian enzyme that may significantly reduce estrogen production. Relative androgen levels rise as a consequence, leading to an increased abundance of hormones like testosterone.

Sudden influxes in testosterone may lead to androgenetic alopecia, a specific type of hair loss caused by hormonal changes in the scalp. Increases in testosterone may fuel the production of DHT, a chemical known to adversely affect the hair follicle’s ability to sustain normal hair growth. Most commonly, DHT causes hair miniaturization; a phenomenon in which hair becomes thinner and finer over time. Eventually, miniaturization turns in to all-out hair loss as DHT shuts down the follicle completely.

In a guest blog on the Women’s Hair Loss Project, holistic nutritionist and certified health coach Ms. Amy Medling offers the following tips for overcoming PCOS naturally (ii):

1. Sizzle in the kitchen. According to Ms. Medling, one of the best ways to get back-on-track is to pay close attention to diet. By cooking your own food, you can be sure to use high quality sources that are rich in vitamins, minerals, and nutrients that promote healthy hair.

2. Have discriminating tastes. “Only clean foods allowed in your temple,” Ms. Medling explains. Again, emphasis is placed on seizing control of the quality and nutritional content of each meal.

3. Move it. Not only does physical exercise promote healthy hormonal balance, but it also makes you feel well. Daily exercise and sun exposure can do wonders for reducing stress, which may also decrease the incidence of Telogen Effluvium (stress induced hair loss).

Treatment Options: Restoring Hair Loss Caused by PCOS

Today, a number of procedures are available to women who experience hair loss from PCOS. In addition to improving diet and exercise regimens, women may explore the following options under the guidance of a qualified hair transplant surgeon and clinic:

1. Hair Loss Evaluation. An expert evaluation is essential in diagnosing the root cause of hair loss as well as identifying the most effective course of treatment.

2. Prescription Hair Loss Medications. For women, prescription hair loss treatments like Rogaine® (Minoxidil) may be effective in slowing hormone-induced hair loss.

3. Surgical Hair Restoration. Today, highly refined methods of surgical hair restoration are available to reverse the signs of baldness in a beautiful and all-natural way. Follicular unit extraction procedures are among the most effective, transplanting patients’ real hair to thin or bald areas to produce an authentic end-result with minimal discomfort.

4. ARTAS® System Hair Transplant. Our Institute is proud to be 1 of just 17 clinics in the United States to offer the revolutionary new ARTAS® System by Restoration™ Robotics. A physician-guided robot system, the ARTAS empowers our surgeons to conduct FUE transplants with unparalleled accuracy, consistency, and precision.

Exclusive Interview: Watch as Dr. Rose presents the ARTAS System to CBS Miami.

At the Hair Transplant Institute of Miami, we hold our patients’ desire for a full and natural head of hair in the highest regard. Our team works diligently to ensure each patient feels comfortable and confident during each visit, from evaluation to procedure and post-procedure follow-up.

We invite you to learn more about hair loss evaluations at our Institute, or contact our friendly front desk at 305.925.0222.

Sources:

(i) “Amy Medling, the PCOS Diva.” Women’s Hair Loss Project. Accessed 3 March 2013.

(ii) See above.

Birth Control Pills and Hair Loss

Birth Control Pills and Hair LossDoes ‘the pill’ cause hair loss? The topic of birth control and hair loss is as old as the medication itself, dating back to the 1960s when oral contraceptives were first introduced to American women. Unfortunately, women are often surprised to learn that common side effects of birth control may include hair loss. Those who consider taking birth control must also realize that contraceptives may cause a variety of additional side effects, and they do not protect against sexually transmitted diseases.

Learn More. To learn more about birth control and specific side effects, please consult your physician. Always seek the guidance of a licensed medical professional before making any changes to diet, exercise, or prescription medication regimens. The following article is meant to provide a basic overview on oral contraceptives, hormones, and hair loss. It is not a substitute for the expert opinion of a licensed professional.

Which Birth Control Pills Are Most Likely to Cause Hair Loss?

To understand which birth control pills are most likely to cause hair loss, it is first helpful to learn the make-up and basic function of each option. Birth control prevents pregnancy by using different combinations of hormones to suppress ovulation and/or prevent conception. Generally, an oral contraceptive can be characterized by the number of hormones it contains. Combination birth control, for example, contains both estrogen and progestin. The Minipill, by contrast, contains only progestin.

Combination Birth Control vs. Minipill: Which Is Best?

In general, hair loss caused by ‘the pill’ is most often a side effect of hormonal fluctuations. In most cases, birth control causes a relative increase in androgen levels. This may cause a corresponding increase in DHT production, which researchers believe shrinks the hair follicle and causes hair miniaturization. Once this happens, the hair becomes thinner and finer over time. Eventually, it may cease to grow altogether.

Since combination birth control pills contain both progestin and estrogen, they may help to keep androgen levels in check. For this reason, physicians may recommend combination birth control medications to women whose genetics or family history makes them predisposed to hormonally induced hair loss. The minipill, on the other hand, contains no estrogen and may cause a greater relative rise in androgen. With greater fluctuation comes increased sensitivity to hormones (like androgen), which may ultimately contribute to hair loss both during and after birth control use.      

The Androgen Index: Identifying Which Pills Are Least Likely to Cause Hair Loss

The Androgen Index is a way of describing the impact a birth control medication may have on relative androgen levels. By choosing a medication with a low Androgen Index, you may limit your chance of experiencing hair loss (i).

According to the American Hair Loss Association, the following list orders birth control from lowest Androgen Index (1) to highest (20):

  1. Desogen
  2. Ortho-Cept
  3. Ortho-Cyclen
  4. Ortho Tri-Cyclen
  5. Micronor
  6. Nor-Q D
  7. Ovcon-35
  8. Brevicon/Modicon
  9. Ortho Norvum 7/7/7
  10. Ortho Novum 10-11
  11. Tri-Norinyl
  12. Norinyl and Ortho 1/35
  13. Demulen 1/35
  14. Triphasil/Tri-Levien
  15. Nordette
  16. Lo/Ovral
  17. Ovrette
  18. Ovral
  19. Loestrin1/20
  20. Loestrin 1.5/30

High Risk Contraceptives. According to the American Hair Loss Association, the following contraceptives have significant potential for “causing or exacerbating hair loss” (ii):

  1. Progestin Implants, like Norplant.
  2. Hormone Injections, like Depo-Provera.
  3. Skin Patch, like Ortho Evra.
  4. Vaginal Ring, like NuvaRing.

Hair Loss Evaluation, Diagnosis, and Treatment

If you are suffering with hair loss, you are not alone. Nearly 2/3rds of all males experience symptoms of balding, and an estimated 20 million American women experience symptoms of thinning by adulthood.

At the Hair Transplant Institute of Miami, we hold our patients’ desire for a full and natural head of hair in the highest regard. We are home of South Florida’s most talented transplant surgeons, microscopists, nurses, and staff. Our team works diligently to ensure each patient feels comfortable and confident during each visit, from evaluation to procedure and post-procedure follow-up.

Early diagnosis is key to full, effective, and natural hair restoration. We invite you to learn more about hair loss evaluations at our Institute, or contact our friendly front desk at 305.925.0222.

Sources:

(i) Birth Control and Hair Loss. American Hair Loss Association. Accessed 25 February 2013.

(ii) Oral Contraceptives. American Hair Loss Association. Accessed 25 February 2013.

Norwood Classification: Understanding Male Pattern Baldness

Norwood Classification- Understanding Male Pattern BaldnessNo Hair to the Throne, the headline read, commenting on Britain’s most eligible bachelor (i). POOR Prince William is losing his crowning glory it continued, mocking the 28 year old for displaying early signs of male pattern baldness. Of course, Prince William is not alone. An estimated 65% or more males suffer with signs of hair loss.

Most times, male pattern baldness is the result of hormonal changes that significantly impair the ability of the hair follicle to sustain natural hair growth. Termed androgenetic alopecia, this condition causes hair miniaturization, a phenomenon in which hair becomes thinner and finer each time it progresses through the growth cycle. Eventually, the hair falls out and ceases to grow entirely.

Psychological Distress. Studies indicate that hair loss may have a profoundly negative affect on not just self image, but on interpersonal interactions and professional life as well. The color, volume, and thickness of hair are major characteristics that affect how others perceive an individual. When compared to individuals with a full head of hair, those with thin or balding areas are often perceived as weaker, older, and less physically attractive. Now, that’s not to say that bald men are not confident. Our culture is filled with icons like Vin Diesel, Dwayne “The Rock” Johnson, and others who enjoy a “bald” look and wear it with confidence.

However, if hair loss is negatively impacting your personal, social, or professional life, there’s a problem. Fortunately, male pattern baldness tends to progress in a predictable pattern over time, allowing hair transplant surgeons to provide expert evaluations and treatment recommendations that will produce natural, long-lasting hair where once was only balding scalp.

Norwood Classification: Stages, Signs, and Symptoms

The Norwood Classification is a system that professionals use to characterize male pattern baldness. Depending on the location and the severity, pattern baldness is classified according to 1 of 7 stages. This helps hair surgeons understand both the extent of the current condition as well as the pattern in which balding is most likely to follow. These two variables play a critical role in determining which hair loss treatment options are capable of restoring areas of the scalp that are thin or completely bald.

The Norwood Classification also provides a framework for understanding how the patient’s baldness may progress. This becomes a very important variable when the patient chooses a hair transplant procedure. Understanding how baldness may progress enables the surgeon to deliver a beautifully natural-looking end result by strategically restoring areas that are thin, balding, or susceptible to future hair loss.

The 7 stages of the Norwood Classification are shown below. Each stage depicts a unique circumstance in which hair is thinning, shedding, or balding in specific areas:

Norwood Classification for Male Hair Loss

Female Hair Loss: For women, pattern baldness progresses in a very different manner. A unique classification system is used to characterize the stages of female hair loss, called the Ludwig Classification. Click the following link to learn more about the Ludwig Classification.

Hair Loss Evaluation, Diagnosis, and Treatment

At the Hair Transplant Institute of Miami, we hold our patients’ desire for a full and natural head of hair in the highest regard. We are home of South Florida’s most talented surgeons, microscopists, nurses, and staff. Our team works diligently to ensure each patient feels comfortable and confident during each visit, from evaluation to procedure and post-procedure follow-up.

Home of the ARTAS® System

In an effort to provide only the newest, safest, and most advanced procedures to our patients, the Hair Transplant Institute is proud to announce the arrival of the ARTAS System for hair transplant. Learn more about the ARTAS System, a physician-guided robotics technology that enables our team to deliver beautiful restoration results with unmatched precision, accuracy, and consistency.

Sources:

(i) No Hair to the Thrown. The Sun. Accessed 18 February 2013.

Ludwig Classification: Diagnosing Female Hair Loss

Ludwig ClassificationHair loss may have a profoundly negative impact on all aspects of life. Individuals who experience hair loss may find it difficult to feel confident, positive, and secure in both professional and personal environments. According to statistics gathered by a variety of national and international health institutions, women are particularly susceptible to hair loss, as well as the negative social and professional side effects that may develop as consequence.

It is estimated by the National Institute of Health (NIH) that fewer than 45% of women go through life without experiencing some degree of hair loss (i). The NIH also reports that women who suffer with hair loss may experience mild to extreme psychological distress, as well as generally impaired social functioning (ii). To aid in the diagnosis and treatment of hair loss among women, hair transplant surgeons and specialists use the Ludwig Classification.

Using the Ludwig Classification to Diagnose & Treat Female Hair Loss

The Ludwig Classification separates female pattern baldness (androgenetic alopecia) into 1 of 3 unique stages, referred to as the Ludwig Scale. By classifying hair loss according to severity, the Ludwig Scale helps both patients and physicians to better understand three major factors in the diagnosis and treatment of female hair loss:

  1. The degree to which hair has already been lost.
  2. The potential for additional hair loss in the future.
  3. The best course of treatment.

The Ludwig Scale

The Ludwig Scale uses 3 different classifications, or Types, to diagnose the severity of female hair loss. From left to right in the image below, these Types include Type I, Type II, and Type III:

Ludwig_Classification_for_Diagnosing_Female_Hair_Loss

Type I. In this stage, hair loss is considered to be mild. Most women may have difficulty noticing that hair loss has occurred, as the frontal hairline remains relatively unaffected. Hair loss may occur on the top and front of the scalp, however. Such hair loss may be noticeable when the hair is parted down the center of the scalp, as more and more scalp will become visible over time.

Type II. Type II hair loss is considered moderate. In this stage, women may notice each of the following: Thinning, shedding, general decrease in volume, and a center part that continues to widen over time. Depending on the severity, a hair transplant procedure may be a viable option for women who exhibit a Type II classification.

Type III. Type III is the final and most extreme classification of female hair loss. In this stage, hair is so thin that it has difficulty camouflaging the scalp, rendering it visible to the naked eye. This may be worsened by a number of factors, including hair miniaturization, progressive thinning, and extensive loss.

Learn More About Identifying Female Hair Loss

To learn more about identifying female hair loss, readers may visit the following guide on the Miami Hair Blog:

Women and Hair Loss: Top 4 Signs

Schedule a Hair Loss Evaluation

Early detection, diagnosis, and treatment provide the best chance of restoring hair to its naturally full, resilient, and beautiful state. To move forward with a hair loss evaluation, schedule an appointment with the Hair Transplant Institute of Miami. Our team represents South Florida’s finest surgeons, registered nurses, and technicians, each of whom hold your pursuit of a fuller head of hair in the highest regard.

Readers may also call our Institute at 305.925.0222 to speak directly with a member of our team.

References for this health report include:

(i) Female Pattern Hair Loss: Current Treatment Concepts. National Institute of Health. Accessed February 10th, 2013.

(ii) See above.

Dr. Rose Presents ARTAS® to CBS Miami

Dr. Rose Presents ARTAS® to CBS MiamiAs our Institute became 1 of just 15 clinics in the nation to offer the revolutionary new ARTAS® System for hair restoration, South Florida residents have become increasingly curious as to how the system works, and why it is more proficient than traditional FUE hair transplant procedures. Last month, Dr. Rose reached out to these individuals, presenting an exclusive interview with CBS Miami about the futuristic hair loss solution.

To learn more about the ARTAS System, readers are invited to schedule an appointment online or contact the Hair Transplant Institute of Miami directly at 1-877-443-9070. Our Institute represents South Florida’s finest hair transplant surgeons, and we hold your pursuit of a fuller, natural-looking head of hair in the highest regard.

CBS Exclusive: ARTAS® System at the Hair Transplant Institute

In the video above, one of our patients explains his experience with the ARTAS System. Our patient began experiencing hair loss at a very early age, which is not entirely uncommon among young men. By age 35, it is estimated that roughly two-thirds of all American men experience some degree of hair loss. Androgenetic alopecia, a genetic condition that causes the phenomenon of hair miniaturization, is one of the leading causes. For many of these individuals, a hair transplant procedure is the most effective means of restoring areas of baldness with real hair that is vibrant, lasting, and all-natural.

Our patient chose the ARTAS System for its advanced ability to produce a transplant with greater accuracy, precision, and consistency compared to traditional methods. Moreover, the ARTAS System extracts donor hair via follicular unit extraction (FUE), a refined process that does not leave a linear scar through the donor area. This was another major reason the procedure was chosen, our patient tells CBS. Following the procedure, our patient can wear his hair very short without exhibiting any signs that a transplant has been performed, like linear scars.

Best of all, our patient explains that during the procedure he felt no pain at all. Although a traditional FUE hair transplant does not cause much discomfort at all, the ARTAS System reduces feelings of discomfort to a nearly undetectable level.

Because the technology uses digital imaging to continuously locate the best hair follicles for transplant, Dr. Rose is able to extract follicular units with unparalleled precision, causing very little scarring or trauma to the scalp. Turnaround time is reduced, meaning that patients may return to their normal day-to-day activities more quickly.

Getting to Know ARTAS®

Would you like to get better acquainted with the ARTAS System? Below are a few of the most common questions our patients have about this revolutionary new piece of technology. For a more in-depth Q&A, readers are invited to visit our guide, Frequently Asked Questions About ARTAS Hair Transplant.

How does ARTAS differ from traditional transplant procedures?

ARTAS combines high resolution digital imaging with advanced robotics technology to enable our physicians to locate and extract follicular units with greater accuracy and precision compared to traditional transplant methods. Of course, each ARTAS procedure is always conducted under the control of an experienced hair transplant surgeon to ensure patient safety and individual results are held in the highest regard.

Is the end-result natural in appearance?

One of the greatest advantages of the ARTAS System is the way in which it targets follicular units for transplantation. Not only does the technology identify prime candidates (follicular units) for transplant, but it also selects them in a randomized fashion. As a result, there is virtually know sign of extraction in the donor area, preserving its natural appearance.

Is the transplant permanent?

ARTAS System procedures are almost always permanent. Transplanted hair has great potential to last a lifetime, as it is harvested from the rear of the head in a minimally-invasive manner that causes very little trauma to the scalp.

Learn More About the ARTAS® System

If you experience hair loss, you are not alone. More than 60% of adult males experience symptoms of baldness by age 35, and millions more females experience shedding, thinning, or loss over the course of their life. Today, hair loss is more easily detected and treated than ever before. And with technologies like the ARTAS System by Restoration Robotics, men and women may choose a procedure that produces beautiful, natural-looking results with minimal disturbance to personal life.

To learn more about the ARTAS System, readers are invited to schedule an appointment online or contact the Hair Transplant Institute of Miami directly at 1-877-443-9070.

Sources for this article include:

(i) High-tech Transplant Procedures for Hair Loss. CBS News, Miami. Accessed January 29, 2013.

New Hair Loss Gene Discovered: APCDD1

New Hair Loss Gene Discovered- APCDD1Scientists have identified a new gene that may help future hair transplant surgeons provide non-hormonal treatments for hair loss. The discovery is a culmination of efforts from research teams across America, including those from Columbia University, Rockefeller University, and Stanford. Researchers have named the gene adenomatosis polyposis down-regulated 1, or APCDD1.

The discovery of the APCDD1 gene is important to researchers, surgeons, and individuals who suffer with a variety of hair loss conditions. The gene seems to play a role in the progressive hair loss experienced by individuals with hereditary hypotrichosis simplex, a rare condition that may manifest itself in the early years of childhood.

Commenting on the study, lead author Angela M. Christiano, Ph.D. explains:

Through their analysis the research team found a common mutation in the APCDD1 gene that is located on a specific region of chromosome 18. Previous studies have shown chromosome 18 to be involved in other forms of hair loss including alopecia areata and androgenetic alopecia. (i)

Dr. Christiano is a professor of dermatology, as well as genetics and development, at the Columbia University Medical Center. For additional information, readers may visit Dr. Christiano’s faculty page on Columbia.edu.

Although the gene seems to play a causal role in a very different type of hair loss, researchers believe studying the APCDD1 gene may eventually aid in the treatment of male and female pattern baldness, as well as other types of hair loss. This is due to the fact that APCDD1 causes hair loss through a process called hair miniaturization, which is the same process through which male pattern baldness progresses.

APCDD1, Hair Miniaturization, and Hair Loss Treatment

To understand the concept of hair miniaturization, it is helpful to first understand how hair grows. Throughout our lifetime, hair grows from follicles located just below the skin. Follicles are the foundation through which hair receives the support, oxygen, and nutrients to grow. Hair grows in three distinct cycles: The growth phase, the shedding phase, and the resting phase. Hair loss professionals may refer to each of these stages as the anagen phase, catagen phase, and telogen phase, respectively. It is estimated that each strand of hair goes through a full cycle of growing, shedding, resting, and re-growing about 10-20 times over the course of a person’s lifetime.

Hair miniaturization is a phenomenon in which hair becomes thinner and finer each time it progresses through the growth cycle described above. Eventually, the hair follicle may even become dormant, in which case new hair growth will cease entirely.

In this study, researchers found that the gene APCDD1 inhibits a specific signaling pathway through which hair growth is directed. Researchers refer to the pathway as Wnt, and it is believed that inhibiting this signaling process may prevent hair miniaturization and pattern baldness from developing. Moreover, Dr. Christiano believes the discovery could make advanced hair loss treatment a reality for a much broader number of individuals:

Unlike commonly available treatments for hair loss that involve blocking hormonal pathways, treatments involving the Wnt pathway would be non-hormonal, which may enable many more people suffering from hair loss to receive such therapies. (ii)

Connect with the Hair Transplant Institute

Follow Miami_Hair on Twitter or Like Our Facebook Page to keep up-to-date with the latest hair loss news, research, and health guides!

Sources for this report include:

(i) Scientists Identify New Hair Loss Gene – APCDD1. Blog.americanhairloss.org. Accessed January 8, 2013.

(ii) See above.

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