Category: Hair Loss Research
PRP with Different Preparation Systems

Miami Hair Doctors Examine Variability of PRP in ISHRS Forum International

PRP with Different Preparation SystemsNumerous hair restoration doctors have advocated the use of platelet-rich plasma (PRP) as a means to improve hair growth and limit hair loss. The use of PRP for wound healing has been well documented. It has been used for problems ranging from orthopedic injuries to dentistry. 

In this July/August edition of the ISHRS Forum International, Miami Hair doctors, Dr. Paul Rose and Dr. Aron Nusbaum, evaluate the concentration of platelets produced by four different commercially available systems. The platelet counts in the PRP were compared to the whole blood concentration of platelets in each patient. 

The results demonstrated a wide variance in platelet concentrations among the different systems.

Click here for the full PDF article from ISHRS

At the Hair Transplant Institute of Miami, we have created the most comprehensive approach for evaluating and treating patients with hair loss, while providing the very latest in scientific techniques at our state-of-the-art facility. If you are interested in exploring your options for addressing hair loss, please schedule an appointment with the Hair Transplant Institute of Miami today by calling 305.925.0222.



FUE Scarring

Dr. Paul Rose Discusses FUE Scarring in ISHRS November/December Edition

FUE Scarring

In the November/December 2018 edition of the Hair Transplant Forum International (ISHRS), Dr. Paul Rose of the Hair Transplant Institute of Miami authored a case report, reporting on a patient that underwent a prior FUE procedure. 

As one of the originators of the FUE procedure, Dr. Rose holds incomparable experience when it comes to method and accuracy. From his findings, this case report serves to demonstrate that the wounds created by the FUE process can result in scarring after the healing phase. 

Click here for the full PDF article from ISHRS

At the Hair Transplant Institute of Miami, we have created the most comprehensive approach for evaluating and treating patients with hair loss, while providing the very latest in scientific techniques at our state-of-the-art facility. If you are interested in exploring your options for addressing hair loss, please schedule an appointment with the Hair Transplant Institute of Miami today by calling 305.925.0222.

Understanding the Side Effects of DHT Blockers

DHT BlockersFew medications come without the potential for unwanted side effects. Sometimes those side effects are relatively rare or minor. Other times, those side effects, should they occur, may be so significant that they may outweigh the benefits the medication is supposed to provide. When it comes to hair loss medication, DHT blockers can pose just such a dilemma. While DHT blockers can help reduce hair loss, they can also reduce sexual function in rare instances, which makes the decision to use them a deeply personal and complicated one.

What is DHT?

Dihydrotestosterone, or DHT, is a derivative of testosterone that has been scientifically linked to hair loss. Typically, due to genetics or other hormonal changes, hair follicles develop a sensitivity to DHT and begin to miniaturize. This process shortens the hair growth cycle and eventually causes new hair to stop growing. As such, individuals with elevated DHT levels may be more prone to hair loss.

Reducing DHT levels is what makes Propecia, one of the most popular pharmaceutical hair loss treatments, so effective. Some studies have shown that Propecia can reduce DHT levels by as much as 70%.

What is the Problem With Reducing DHT Levels?

The problem is that DHT does much more than contribute to hair loss. It also plays a crucial role in male sexual development and mood regulation. When DHT levels are reduced, either intentionally or unintentionally, it can impact these functions in unwanted ways and cause:

  • Impotence
  • Lower sex drive
  • Difficulty achieving orgasm
  • Abnormal ejaculation
  • Gynecomastia (male breast development)
  • Depression

Additionally, since DHT blockers like Propecia affect the body’s hormone system, they should not be handled by pregnant women or women who may become pregnant as it may increase the risk of birth defects in male babies.

How Common are the Side Effects of DHT Blockers?

The good news is that that these side effects only appear in a small minority of men (about one out of every hundred) who use DHT blockers such as Propecia. If any issues do develop with sexual functioning, they are almost always temporary and will return to normal after discontinuing the drug.

As with any medication, you should discuss with your hair loss physician whether DHT blockers or other pharmaceutical treatments offer a viable and effective option for addressing your hair loss issues.  

Call the Hair Transplant Institute of Miami Today to Schedule Your Personalized Hair Loss Consultation

At the Hair Transplant Institute of Miami, we evaluate each hair loss patient with a comprehensive and proven methodology, obtaining a detailed medical history, performing an in-depth scalp examination using state-of-the art diagnostic tools and, if indicated, blood tests to detect any underlying imbalances or deficiencies that may be contributing to the hair loss problem. With this information, we can determine the cause of hair loss and the most effective treatment option, whether it be medication, hair transplant surgery, or other alternatives.

To schedule your personalized hair loss evaluation, contact us online or call our office directly at 305-925-0222.

Vitamin D For Your Hair.

You Need More Vitamin D. So Does Your Hair.

Vitamin D For Your Hair. Vitamin D is a critical nutrient. It bolsters our immune system and wards off illness. It is vital for bone health. Some research suggests that insufficient amounts of vitamin D contribute to depression, heart disease, and cancer. Vitamin D also plays an important role in the strength and growth of hair, and a lack of this nutrient has been linked to alopecia, also known as spot baldness.

Our primary source of vitamin D is the sun (which is why it is sometimes referred to as the “sunshine vitamin”). We can also get vitamin D from foods rich in the nutrient, such as fish, fish liver oil, eggs, and dairy, as well as through supplements.

New Study Suggests Global Vitamin D Problem

While we have known about the importance of vitamin D for a while, a new study is raising alarms about widespread vitamin D deficiency around the world. “The Big Vitamin D Mistake,” a paper by Finnish researchers, argues that current recommended levels of vitamin D are too low, and that “actions are urgently needed to protect the global population from vitamin D deficiency.”

The Vitamin D Council agrees and says that “the current recommendations for vitamin D supplementation (600-800 IU) are far too low to help the majority of individuals to reach healthy vitamin D levels. That is why we recommend supplementing with between 5,000-10,000 IU per day in order to achieve healthy vitamin D levels (40-80 ng/ml).”

Vitamin D and Hair Loss

The key to resilient, strong hair less prone to falling out lies in the follicles. When hair follicles become traumatized, damaged, or otherwise inactive, the growth of new hair stops and pattern baldness begins.

Research suggests that vitamin D, along with the receptors in the skin that bind to the nutrient, plays a significant role in promoting healthy follicles and hair growth while a lack of the vitamin may lead directly to hair loss. A 2014 study published in Molecular Endocrinology found that hair regrew in mice two weeks after introducing vitamin D receptors. Other studies also have made the connection between hair loss and vitamin D.

While we are not yet at the point where we have developed a Vitamin D-based “cure” for baldness, we are definitely at the point where we can say that healthy levels of vitamin D help promote the strength of your hair and reduce the chances of significant hair loss.

Make sure you consult with your physician before making any significant changes to your diet or your vitamin D levels, as too much vitamin D can create other health problems, such as calcium accumulation in the blood which may cause weakness or problems with the kidneys.

Whether as an adjunct to hair restoration treatments or just as part of a healthy lifestyle, a balanced diet rich in key nutrients such as vitamin D can help boost hair growth in addition to improving your overall health and sense of well-being.

Schedule an Appointment for a Hair Loss Evaluation Today

Of course, dietary improvements alone may not stop hair loss or restore your hair to the fullness it once had. At the Hair Transplant Institute of Miami, our skilled physicians diagnose and treat hair loss cases that can’t be reversed at home. Through advanced hair restoration surgery techniques and alternative non-invasive treatments, we can help patients suffering from hair loss.

To receive a personalized evaluation and treatment plan, contact us online or call our office directly at 305-925-0222.

Dr. Paul Rose, MD, JD Published In Dermatologic Clinics


Dermatologic Clinics Dr. Paul RoseAdvances in Hair Restoration
by: Dr. Paul T. Rose

Key points in this article:

• Selection of hair transplantation methodology depends on patient’s goals, type of hair loss, and quality of hair.

• Robotic hair transplantation is the latest frontier in hair restoration.

• Platelet-rich plasma, low-level laser therapy, and stem cells can be used together with hair transplantation to enhance graft survival.

Download full article here:




How to Grow Fuller Hair with Stem Cell Hair Therapy

Researchers Succeed in Growing Hair From Embryonic Stem CellsOur bodies are finely-tuned, intricate machines. Like all machines, they need regular maintenance and occasional repair. Stem cells are the all-purpose handymen of our bodies, available to help restore healthy functioning throughout, including the hair and scalp. Full heads of hair are the result of hair follicles which are constantly regenerating, due in part to the presence of stem cells. But when those stem cells shrink and deteriorate as we age, hair stops renewing and ultimately falls out. That’s why reintroducing an individual’s own stem cell back to the follicles has the potential to create a nourishing environment which may foster regrowth and fight the battle against hair loss.

That is why stem cell therapy for hair loss has become an increasingly popular treatment.

What Does Stem Cell Treatment for Hair Loss Involve?

Safe and effective, the minimally invasive stem cell procedure involves isolating a few ounces of adult stem cells from fat in the abdomen, flanks, or love handles and reintroducing them to the scalp.

Those fat cells are removed from the midsection using a “mini” liposuction procedure. Prior to this approximately 20-minute-long outpatient procedure, a mild oral sedative and local anesthesia is administered, minimizing any pain or discomfort.

Following the liposuction, the medical professionals performing the procedure will isolate the stem cells while you rest. Once isolated, they will then be injected into targeted areas of the scalp, where they will begin their work stimulating hair growth.

What Happens After the Treatment?

The whole treatment process should last approximately three hours. As an outpatient procedure, you will be able to go home shortly thereafter. However, since you will have been under mild sedation, you should arrange for someone else to drive you home. While you may experience some mild soreness after the procedure, you should be able to go back to work the next day.

When Can I Expect to See Results?

It may take a few months before you notice any results, and as this is a relatively new procedure, it is not yet clear how long results will last. However, the team at the Hair Transplant Institute of Miami is optimistic of long-term hair regrowth potential, particularly with ongoing treatment. Stem cell treatment can be used in conjunction with hair transplant surgery, platelet-rich plasma (PRP) injections, topical treatments or low-level laser therapy (LLLT) to increase your odds of success.

To consult with Dr. Bernard Nusbaum and Dr. Paul Rose about whether Miami stem cell treatment may be right for you, call our office at 305-925-0222 or contact us online to book your appointment.  

New Hair Loss Gene Discovered- APCDD1

New Research Reveals Over 250 Genetic Signals for Hair Loss

New Hair Loss Gene Discovered- APCDD1While male pattern baldness affects most older men, research on genetic predisposition to baldness has been minimal – until now. In a recent study published in the journal PLOS Genetics, a Scottish research team from the University of Edinburgh found nearly 300 genetic ties to hair loss, helping identify potential chromosomal markers of male pattern baldness.

The study analyzed over 52,000 male participants between the ages of 40 and 69-years-old. This is the largest genetic report on male pattern baldness to date.

“We identified hundreds of new genetic signals,” said Saskia Hagenaars, co-lead author of the study, in a news release. “It was interesting to find that many of the genetics signals for male pattern baldness came from the X chromosome, which men inherit from their mothers.”

Based on the genetic variants between a discovery sample (40,000 subjects) and a target sample (12,000 subjects) that distinguished patients with no hair loss and severe hair loss, the team developed an algorithm to forecast who may develop male pattern baldness. The higher the patients genetic (polygenic) score, the more likely they were to suffer from male pattern baldness. Among participants with a sub-median score, 14 percent showed severe hair loss while 39 percent had no hair loss. Meanwhile, 58 percent of patients who scored within the top 10 percent showed moderate-to-severe hair loss.

genetic hair loss

Fig 3. Distribution of hair loss by male pattern baldness polygenic score decile in the independent sample. Source: PLOS Genetics

For the most part, the genes identified are associated with hair structure and development. These findings could support early diagnosis and better treatment of male pattern baldness in the future.

 “We are still a long way from making an accurate prediction for an individual’s hair loss pattern,” said principal investigator Dr. Riccardo Marioni. “However, these results take us one step closer.”

As noted in the report, male pattern baldness affects approximately 80 percent of men by age 80. Balding can lead to substantial emotional issues, including diminished self-confidence, social isolation and depression. Past research has also linked baldness to an increased risk of prostate cancer and cardiovascular disease.

Download and read the full study here.

Researchers Succeed in Growing Hair From Embryonic Stem Cells

Can Stem Cells Treat Hair Loss?

Researchers Succeed in Growing Hair From Embryonic Stem CellsThanks to stem cells, hair follicles are constantly regenerating. When they stop renewing, hair loss ensues. In the effort to target hair loss at the root, research shows that re-introducing a patient’s own stem cells to the follicle creates a nourishing environment to foster regrowth and fight the battle against hair loss.

In addition to hormonal changes associated with androgenetic alopecia, stem cells begin to shrink and deteriorate as we age. Per a recent Japanese study¹, stem cells that help promote hair renewal begin to wear and tear overtime, limiting the potential for follicle restoration. In addition, the follicles face miniaturization or shrinkage, making it difficult for new hair to grow. Aside from getting older, sun damage and chemical exposure can expedite stem cell damage.

Stem Cells for Hair Loss Treatment in Miami

The minimally invasive stem cell procedure involves a mild oral sedative and local anesthesia, making the process quick with little discomfort. Using a liposuction tool, we derive fat cells from the belly, flanks or love handles and extract the stem cells that will later foster hair growth. We then inject this concentrated stem cell sample onto the scalp.

Although stem cell treatment for hair growth is a relatively new procedure, the team at the Hair Transplant Institute of Miami is optimistic of long-term hair regrowth potential, particularly with ongoing treatment. Stem cell treatment can be used in conjunction with hair transplant surgery, platelet-rich plasma (PRP) injections, topical treatments or low-level laser therapy (LLLT) to increase your odds of success.

To consult with Dr. Bernard Nusbaum and Dr. Paul Rose for Miami stem cell treatment, call our office at 305-925-0222 or book your appointment using our online form. For non-Miami residents, we partner with area hotels to minimize lodging costs for our patients. To receive an exclusive Miami hotel discount, contact us after scheduling your procedure for a corporate rate code.



Adrenal Glands, Stress Hormones, and Hair Loss

The Science Behind Stress-Induced Hair Loss and Telogen Effluvium

Adrenal Glands, Stress Hormones, and Hair LossThe unwelcome feelings of stress and anxiety creep up when you least expect them. While intermittent feelings of worry are relatively normal, damaging stress levels are on the rise. These feelings of despair and anguish sometimes provoke thinning or shedding on the scalp. Stress-induced hair loss, called telogen effluvium (TE), can be short-lived or long lasting. Thinning or shedding inadvertently caused by anxiety and trauma is not only frustrating, but worrisome. In addition, trichotillomania is a less common but very serious hair loss condition perpetuated by stress. Unlike TE, patients suffering from trichotillomania actively pull hairs out habitually when facing stress and anxiety to cope.

A 2014 national poll from NPR in partnership with the Robert Wood Johnson Foundation and the Harvard School of Public Health found more than one in every four Americans suffered great deals of stress the month prior to the survey. Half of those adults, or 115 million people, experienced a major stressful event that year. [1] Per the Anxiety and Depression Association of America, anxiety disorders – often explained as chronic high stress and worry – are the most common mental disorder in the United States. Anxiety affects 40 million adults in the U.S., or 18 percent of the total national population. [2]

The American Hair Loss Association says TE and stress-induced hair loss is likely the second most common form of hair loss seen by dermatologists. [3] Although little research has been done to help physicians understand why some patients see hair loss because of stress while others do not, three possible cause and effect scenarios exist:

TE Scenario 1: Environmental factors shock the hair follicle into a resting state. Because the follicles are not actively producing more hair to replace ordinary shedding, patients see diffuse patterns of thinning on the scalp. The effects of environmental “shock” show up two to three months after a major life event. Depending on the duration of the event, follicles can return to their normal healthy state without surgical intervention. Patients usually see their condition clear up in less than six months with full regrowth.

TE Scenario 2: Hair follicles enter their resting state as normal but do not regenerate properly, resulting in gradual hair loss. Rather than return to the anagen phase of hair growth, the follicles remain in the telogen state for prolonged periods of time. Thus, fewer anagen, or active, hair follicles are available. Because this scenario is prolonged, patients may not see immediate thinning. This is more common in individuals with chronic anxiety conditions.

TE Scenario 3: A less discussed form of telogen effluvium occurs when hair follicles go through truncated cycles. This results in persistent shedding and thinning hair.

Many short-term hair loss cases are considered normal. For instance, many women experience short-term hair loss after giving birth due to fluctuating hormone levels – a condition called postpartum alopecia. Most women regrow their hair normally a few months later. Certain vaccines, antidepressants, extremely low-calorie diets and physical trauma are also common environemntal triggers of TE. Chronic illness, particularly chronic stress and nutritional deficiencies, are alternative instigators. Research shows a link between tension, hair follicle biochemistry changes and increased resting (telogen) hair follicles.

Treating Stress-Induced Hair Loss and TE

Luckily, treatments for telogen effluvium are available. Assuming your hair loss is stress-induced, regular exercise, therapy and meditation can help. When a specific cause is not determined and stress relief does not reverse telogen effluvium, doctors resort to treatments such as low-level laser therapy (LLLT). In cases where stress-induced hair loss transforms into an enduring condition, many patients turn to hair loss surgery.

At the Hair Institute of Miami, we welcome patients suffering from stress-induced hair loss to undergo a comprehensive evaluation. Our treatment plans include low-level laser therapy (LLLT) caps and advanced follicular unit transplant (FUE) procedures. Either alone or in conjunction with one another, LLLT and FUE helps patients suffering from lingering telogen effluvium regain their confidence and sense of well-being. Call us today at 305-925-0222 to schedule your personalized hair loss consultation in Miami.






What is Alopecia Areata?

Hair-Transplant-Surgery-for-Women-Rapidly-Increases-in-UKNot to be confused with androgenetic alopecia, or hereditary hair loss, alopecia areata is an autoimmune disorder. It can lead to unpredictable hair loss, and unfortunately modern medicine hasn’t figured out exactly why it occurs.

Alopecia areata is more common than you might assume, affecting 2 percent of Americans, or roughly 6.5 million people. Unlike hereditary hair loss which generally manifests later in life, alopecia areata typically occurs before the age of 30.

Alopecia Areata Causes

Alopecia areata can be frightening. Hair loss progresses abruptly and rapidly. One in five patients who suffers from alopecia areata has a family member with the same condition. In addition, individuals who have a personal or family history with other autoimmune disorders could be more prone to developing alopecia. Medical scientists do not believe the condition is caused by stress, but high anxiety could trigger alopecia to begin. Individuals who suffer just a few patches of hair loss often undergo a full recovery. Unfortunately, total hair loss is more difficult to bounce back from.

Essentially, this condition is caused by the immune system and white blood cells attacking the hair follicles, causing them to shrink and subsequently slow down hair production. Alopecia begins in hair loss of quarter-sized patches. The hair follicles are not destroyed and can regrow strands as soon as the inflammation dwindles.

Symptoms and recovery

For most people, the condition doesn’t progress past this point, but many patients see total hair loss across the scalp, face and body. Total hair loss on the scalp driven by this autoimmune disorder is referred to as alopecia totalis, while total hair loss across the body is called alopecia universalis. Both of these more severe conditions affect about 10 percent of individuals suffering from alopecia.

Some patients say they have itching or burning prior to losing hair. Other symptoms sometimes become apparent in the nails with dents, white spots, lines, rough texture, dullness, and thinning or splitting.

Around 30 percent of patients suffer alopecia long-term or experience repetitive cycles of patchy hair loss. Half of patients recover within the first year, although multiple episodes are common. Sometimes, the recovered hair is white instead of the patient’s natural color.


Unfortunately, there is no cure for alopecia. However, doctors can prescribe corticosteroids to suppress the immune system. The most common way to take these anti-inflammatory drugs is through local injections, but can also be taken via ointment or oral tablets.

Doctors may recommend Minoxidil, or Rogaine, as a treatment method. While topical treatments can help to an extent, it will not stop your body from creating new bald patches. Some patients turn to homeopathic medicines and acupuncture, but medical evidence does not fully support these methods.

For more information on alopecia areata and other types of hair loss that could be treated with hair restoration or low-level laser therapy, contact the Miami Hair Transplant Institute at 205-448-9100.